Pipeline Strategy & New Target Discovery Intern, Summer 2023

Schrödinger's mission is to revolutionize drug discovery through the use of breakthrough computational methods applied to drug design. Schrödinger Therapeutics Group is seeking outstanding individuals to join our target discovery and pipeline strategy team as interns for a minimum of 12 weeks (with potential for extensions up to one year or full time employment if the opportunity arises). Interns will be tasked with critically reviewing literature and other data sources, identifying unmet needs, new target ideas and synthesizing the information into proposals, and clearly presenting their insights to the team. The work is highly immersive within a collaborative, multidisciplinary team.
Our drug discovery group of over 80 scientists includes biologists, structural biologists, modelers, computational chemists, medicinal chemists, and crystallographers with decades of combined drug discovery experience. The group is supported by more than 100 software developers and engineers. Schrodinger has co-founded several biotech companies leading to exciting therapeutics and approaches, such as Nimbus (recent TYK2i acquisition by Takeda), Morphic Therapeutic (Phase 2 first-in-modality integrin inhibitor for IBD), and Structure Therapeutics (structure-based GPCR company).Four of the programs Schrödinger has worked on in the past 7 years have progressed into the clinic and one has received FDA approval.
Who Will Love This Job:

• A self-motivated individual who will analyze therapeutic area landscapes and identify unmet needs leading to new target opportunities for Schrodinger's drug discovery group.
• Individuals with diverse interests and backgrounds are interested in life sciences and biotech.
• An excellent communicator with the ability to collaborate with colleagues with expertise across a number of disciplines

What You Will Do:

• Perform landscape analysis of therapeutic area(s) and identify unmet needs.
• Build target proposal packages, including therapeutic rationale, target patient population, competitive landscape, deals analysis, strengths/weaknesses/opportunities/threats, risks, etc. for targets that are fit for Schrodinger's drug discovery platform.
• Collaborating with different teams across the company and presenting proposals to leadership teams.

What You Should Have:

• Strong scientific background (MS or ongoing/recent PhD), postdoc, medical background (MD), or MBA students with relevant experience, is highly desired.
• Experience in identifying new biological targets and unmet needs for therapeutic indications via primary and secondary sources.
• Prior experience of internships in venture capital, equity research, company creation, and/o consulting is highly desired.
• Excellent verbal and written communication skills, presentation skills, and organizational skills.
• Ability to interact with multidisciplinary teams including biologists, structural biologists, and chemists
• Ability to work in a fast-paced and quickly changing environment
• Preferable to have some experience with one or more of the following: small molecule drug discovery, targeting challenging or "undruggable" proteins, target validation, molecular pharmacology, and/or structural biology, mapping protein binding sites etc.

Cover Letter
Please note that this is a really important part of the application. If you have a different background but have great potential and want to make the case why we should consider you please include that in the cover letter. Every candidate should include the following in the cover letter.

• What makes you uniquely qualified to be considered for this position?
• What is an achievement that you are most proud of?
• What recent discovery or innovation in a therapeutic area are you excited about and why?
• What unmet need or therapeutic area are you most passionate about solving?