Postdoctoral Fellow - Oncogenesis, Stem Cell Biology, Cell Signaling, Transcription Regulation, Hormone Action & Disease Models

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. ZJ Sun at Beckman Research Institute of City of Hope, one of a prestigious group of NCI-designated Comprehensive Cancer Centers.

The Sun laboratory examines stem cells and stem cell niches in prostate development and tumorigenesis using "cutting-edge" and unbiased analytic tools and unique and innovative genetically engineered mouse models. The Postdoctoral Fellow will join a highly productive lab to directly work on the novel and ongoing projects to uncover cell signaling pathways, and related gene-expression and genomic and epigenetic alterations that regulate the prostatic epithelial-stromal interactions in development and tumor development and progression.

Key Responsibilities include:

• The successful applicant will investigate steroid hormone action, transcriptional control, and cell signaling in development and tumorigenesis.
• The Fellow will develop and use novel and advanced biological approaches, and genetically engineered mouse models to uncover gene-expression and genomic and epigenetic alterations in cancer initiating cells in order to understand mechanisms underlying tumor initiation, progression, and metastasis.

Basic education, experience and skills required for consideration:

• Ph.D. or M.D/Ph.D. degree in Cancer Biology, Molecular Biology, Genetics, Biochemistry, Cell Biology, or a related field.
• A proven track record of creativity and productivity.
• Highly self-motivated, strong desire to learn, and have excellent communication skills.
• Previous experience with mouse models of human diseases, cancer biology, molecular biology, or genetics is highly desired, but not required.

Additional Information:

• To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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• Posting Date: Dec 17, 2021
• Job Field: Research
• Employee Status: Regular
• Shift: Day Job