Principal Scientist

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Summary

Working within Translational Medicine Team, the candidate will be part of the translational group based in Summit NJ and will contribute to/manage the scientific and preclinical laboratory component of late-stage hematology programs (phase 2 and beyond). Key responsibilities of this role are to lead from the bench for the preclinical support of asset programs through mechanism of action-based studies, differentiation from standard of care molecules, combination rationale and resistance mechanisms. He/She will work with translational scientists, disease leaders within translational medicine and thematic research centers in early development within the company.

Responsibilities

• Leads preclinical/laboratory support component of late stage BMS compounds to support annual goals and objectives for the Heme Translational Medicine group (for internal /external, collaborations, compound specific plans etc)
• Responsible for delivering data in support of translational strategies including combination strategies, resistance mechanisms, and drug differentiation
• Work with bioinformaticians, members of disease and clinical teams to identify and validate novel therapeutic targets
• Keep up with scientific literature and adopt novel technologies to tackle scientific questions
• Assists on and manages preclinical collaborations across the pipeline compounds for clinical assets
• Assists in managing key strategic and/or collaborative projects along with TM scientists
• Communicates regularly and prepares and makes presentations within the department, externally and to senior management as required

Basic Qualifications:

• Bachelor's Degree
  • 8+ years of academic and / or industry experience

Or

• Master's Degree
  • 6+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences
  • 4+ years of academic and / or industry experience

Preferred Qualifications

• PhD in cellular or molecular biology, cancer biology, biochemistry, genetics, or related fields with at least 6 years of relevant work experience. Experience including drug development in an industry setting, especially hematology indications is a plus
• Strong publication record and track record in academic or industry setting, leading innovative efforts within the laboratory setting to achieve defined goals and support clinical development
• Excellent communication, managerial and scientific qualities are expected
• Ability to interact effectively across boundaries using influencing and relationship building skills.
• Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals

Technical Skills

• In-depth understanding of cancer biology (hematology a plus), epigenetics, immuno-oncology, clinical landscape, and evolving technologies
• Extensive hands-on experience with molecular and cellular biology techniques as well as cell-based assays, e.g., DNA/RNA purification, RT-RCR, flow cytometry, Western blotting, JESS, InCucyte, CRISPR/Cas9-mediated gene editing, and drug combination assays
• Experience with genomic technologies (e.g., ChIP-seq, scRNA-seq and Perturb-seq) is preferred.
• Strong ability to troubleshoot and optimize novel methods and protocols
• Good understanding of drug development process in an industry setting with clear examples of success
• Ability to work with disease teams/experts to develop preclinical strategies to support clinical development and life cycle management
• Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, and strategic communications
• Proven scientific/project leadership expertise (working in teams, managing collaborations, people/projects)

Other Attributes

• A problem solver who creatively and knowledgeably transcends departmental function to act as a resource to entire research effort and senior managers in development.
• Identifies issues early and proposes innovative solutions.
• Communicates within the larger organization and external community.
• Provides expert guidance to multi-disciplinary teams and senior management.
• A leader whose scope of influence stretches across the company

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as "Transforming patients' lives through science™ ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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