Principal Scientist, Experimental Immunology

Company Description

Biogen’s West Coast Hub, based in South San Francisco, is specifically focused on transforming the lives of patients with severe immune-mediated diseases by developing novel targeted therapies with outsized clinical impact, faster. To accomplish this, we are seeking top talent to join us on our journey.

Job Description

HI-Bio, Inc., a Biogen company, is seeking a highly motivated Principal Scientist in Experimental Immunology to drive the discovery and validation of novel therapeutic targets in autoimmune and inflammatory diseases. The successful candidate will have the opportunity to drive forward multiple discovery programs that encompass target identification and validation, followed by development and application of in vitro and in vivo assays to evaluate therapeutic hypotheses.

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What You’ll Do

• Drive novel target discovery and validation for immune-mediated diseases both as an individual contributor and in collaboration with cross-functional teams.
• Set up and perform cell-based and in vivo assays to establish proof-of-concept for prospective targets, and advance therapeutic candidates for autoimmune and inflammatory diseases.
• Establish outsourcing strategy for specialized experiments to complement in-house work, and manage relationships with CROs for efficient execution.
• Manage associate scientist or scientist-level individuals as needed.

Qualifications

Who You Are

You are passionate about target discovery and validation, and have the ability and experience to execute on critical experiments that enable rapid prioritization of prospective targets. You are motivated to evaluate therapeutic hypotheses in the scientific discipline of experimental immunology.

This position is based in South San Francisco, California and required frequent onsite presence. Candidates must be within commutable distance or able to self-relocate to be considered.

Qualifications

• Ph.D. degree in biology, immunology, or related scientific field with 5-8 years of industry experience. Candidates without a Ph.D. with extensive, highly related experience will also be considered.
• Hands-on experience with novel target discovery using “omics” datasets and target validation is required.
• Experience coordinating discovery efforts across multidisciplinary teams and management of CROs is required.
• Demonstrated track record of independent critical thinking and scientific achievement in discovery biology as demonstrated by publications, patents, or pipeline contributions.

Preferred Skills

• Experience with setting up novel workflows for generating and analysis of “omics” datasets and cell-based assay development for target validation is highly preferred.
• Familiarity with mast cell biology, immune mediated diseases or bispecific antibody characterization is desirable.
• Experience with team leadership and mentorship is considered a plus

Additional Information

The base compensation range for this role is $139,000 - $202,000.  Base salary is determined by a combination of factors including, but not limited to, job related years of relevant experience, internal equity, and location of the job. Additionally, this role is eligible for participation in Biogen’s LTI grants and other incentive programs. Biogen offers a full range of benefits that include medical, dental, life, long and short-term disability insurances, vacation, end-of-year shutdown, and 401K participation and matching contributions.

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.