Research Associate I, Analytical Operations

Research Associate I, Analytical Development
About Capstan Therapeutics
Capstan Therapeutics, Inc. is a privately held biotechnology company dedicated to advancing in vivo cell reprogramming. The core platform technology comprises proprietary targeted lipid nanoparticles (tLNPs) that are composed of LNPs conjugated with a recombinant protein binder, such as a monoclonal antibody. tLNPs are designed to deliver payloads, including mRNA or gene editing tools, capable of reprogramming specific cell types in vivo. The platform technology has the potential to generate transformative therapies with possible applications across a broad range of disease areas, including autoimmune disorders, oncology, fibrosis, and monogenic blood disorders.
The Opportunity
Capstan is seeking a highly motivated Research Associate I to join the Analytical Development team. In this role, you will be responsible for routine testing along with analytical method development/optimization for characterization of our LNPs/tLNPs along with its individual components. This role requires a strong attention to detail with a quantitative/analytical mindset and drive to tackle complex problems in a dynamic environment.
Responsibilities & Duties:

• Perform routine analysis and contribute to development/optimization of methods under supervisor guidance to support characterization of LNPs/tLNPs and subcomponents
• Collaborate with internal and cross-functional teams to ensure data accuracy and reliability. Troubleshoot out of trend results
• Discuss methods/data in team meetings. Actively contribute to improving team operations, analytical procedures, methods, SOPs, etc.
• Support analytical lab operations through equipment mai2tenance, organizing and maintaining inventory, aliquoting and labeling, and other tasks as needed
• Maintain detailed and comprehensive documentation and electronic lab notebook (ELN) entries for all performed experiments and assays
• Prepare data reports and presentations as needed
• Follow safety procedures/guidelines, protocols, and Standard Operating Procedures (SOPs)

Requirements/Qualifications:

• Bachelor’s degree in Analytical Chemistry, Chemistry, Biochemistry, Pharmaceutical Sciences, Bioengineering or other related field with 0-2 years industry experience
• Prior experience with UV-VIS, plate-based assays, ELISA, gel electrophoresis and/or PCR-based assays is strongly preferred
• Prior experience with HPLC, LC-MS, and/or capillary electrophoresis is preferred
• Highly adaptive and comfortable working in a fast-paced, dynamic environment
• Must be detail oriented with demonstrated ability in problem solving and organization
• Strong team player with excellent communication skills and interpersonal skills
• Excellent written and oral communication skills
• Ability to work overtime (as needed) required
• Level will be dependent on candidate qualifications

Salary & Benefits Offerings:

• Salary range is $65,000 - $78,000 year depending on experience
• Performance bonus
• Employee Stock Option Program
• 401(k) Program including an employer matching contribution
• Medical coverage
• Dental coverage
• Vision coverage
• Short- and Long-Term Disability coverage
• Flexible Spending Account (FSA)
• Optional Dependent Care Account
• Paid Time Off (PTO)
• Company Paid Holidays
• Paid Sick Leave
• Employee Assistance Program
• Onsite Fully Stocked Kitchens