Scientist- Bispecifics

We are seeking a highly motivated Scientist to join a dynamic team within the Bispecifics department. You will be focused on supporting the development of cutting-edge Cell & Gene therapies. We hope you are excited to work methodically, independently, and collaboratively in a fast-paced environment. 

As a Scientist within the Bispecifics group, a typical day might include:

• Maintaining and manipulating mammalian cell cultures (immortalized cells and primary cell cultures)

• Harvesting and preparing large numbers of primary T cells

• Designing and cloning retroviral vector constructs. 

• Running cell-based assays to characterize and assess transgene expression and activity: viral transduction, multiparameter flow cytometry, Western blot etc.

• Performing basic molecular biology techniques (DNA/RNA extractions, quantitative PCR (ddPCR), Sanger sequencing etc.)

• Performing basic biochemical/immunological assays (ELISA, MSD, Incucyte)

This role may be for you if you: 

• Have an affinity for cell engineering, process and technology development-focused projects

• Are passionate about innovation and desire to help lead new scientific directions

• You are a quick learner and wish to expand your skill set and learn new techniques

• Are confident with multitasking and adapting quickly to changes in priorities

• Exemplify a strong collaborative spirit and are scientifically rigorous

• Possess a keen attention to detail and time management skills

In order to be considered for this role, you must have at least a BS/MS degree in Immunology, Cellular Biology, Molecular Biology, or a related field and 6+ years of relevant lab experience. Must have experience with multi-color flow cytometry and maintaining cell lines. Experience in generation of CAR-T cells, cell culture maintenance and manipulation (selection, activation, expansion, transfection, viral transduction, cryopreservation) is required. Development of cell-based assays for immunophenotyping (flow cytometry and analysis, MSD/ELISA) and expertise in molecular biology techniques (molecular cloning, nucleic acids extraction, PCR) is strongly preferred. Experience in CRISPR-based gene editing and/or in designing and performing in vivo tumor studies would be a plus. 

$90,700.00 - $148,100.00