Senior Research Associate II, Protein Therapeutics

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At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
 

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Job Description
 

Gilead Sciences has an excellent opportunity for a senior research associate with demonstrated gene-to-protein expertise in the Protein Therapeutics department. As part of our Protein Biochemistry team, the successful candidate will play a crucial role in drug discovery campaigns across Virology, Oncology, and Inflammation therapeutic areas. They will engineer, express, purify, and characterize high-quality proteins, contributing significantly to our mission. The candidate will independently assess and record protein quality attributes using biophysical analytics and routinely present and discuss results with critical stakeholders in cross-functional teams.

Key Responsibilities:

• Small- and large-scale expression and purification (milligrams scale)

• Protein Analytics

• Protocol development for challenging purifications

• Excellent oral and written communication skills

• Collaborating across the team and functions

• Solid background in protein sciences and biochemistry

• Timely and detailed record-keeping

Qualifications:

• Bachelor's degree with 4+ years or Master’s with 2+ years of related experience with hands-on experience in molecular biology and protein expression using E. coli, insect, and mammalian expression systems is required. Preferred experience: 5+ yrs with B.S. or 3+ years with M.S. of industry experience.

• Expertise in protein purification using AKTA instruments is essential.

• Experience with automated and high throughput purifications is ideal.

• Candidate must demonstrate the ability to independently develop and troubleshoot purification protocols and assess protein quality using biophysical analytic tools (SDS-PAGE analysis, Western blot, FPLC, HPLC, MALS, DLS, DSF, Mass Spectrometry).

• Familiarity with structure-based design and engineering of proteins (sequence alignment, protein structure analysis using modeling software) is ideal.

• Strong motivation to work independently and in a team environment and solve challenging problems creatively.

• Ability to multi-task and excel in a fast-paced team environment

• Attention to detail, accurate record keeping, and good lab citizenship practices are essential.

The salary range for this position is: $107,270.00 - $138,820.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.