Postgraduate in Gene Therapy

Summary

We are looking for a highly motivated intern who recently received a M.Sc. degree with a strong scientific drive and interest in cell culture technologies & gene therapy.

About the Role

The intern will advance our adeno-associated viral vectors (AAV) manufacturing platform using diverse molecular & cell biology tools.

Preferred start date: February 2025

Latest start date: March 2025

Duration: 10 months

Please attach a cover letter explaining your motivation for this position and let us know when you are available. Thank you very much.

Key responsibilities:

• Evaluate and improve essential components for the production of AAVs
• Execute state-of-the-art AAV productions and determine quality by ddPCR, WES, capsid quantification and transduction analysis
• Monitor viability, growth and gene expression of cells using appropriate methods such as flow cytometry, NyONE, NGS & qPCR
• Document experiments using electronic lab book and according to line function requirements
• Analyze and collect experimental data & present scientific interpretation in internal meetings

Essential requirements:

• Education: Recent Master graduate (up to 6 months) with a degree in Biotechnology, Biology, Bioengineering, Biochemistry or similar
• Languages: Proficient in English (written and spoken)
• Experience/Professional requirements:
  • Experience in cell culture, desirable HEK (suspension) cell culture
  • Excellent team player

Desirable requirements:

• Good experience in the production of adeno-associated viruses (AAVs) is of advantage
• Experience in ddPCR, qPCR, WES and flow cytometry is of advantage

Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture

Commitment to Diversity and Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Accessibility and accommodation

Novartis is committed to working with and providing reasonable accommodation to all

individuals. If, because of a medical condition or disability, you need a reasonable

accommodation for any part of the recruitment process, or in order to receive more detailed

information about the essential functions of a position, please send an e-mail to

[email protected] and let us know the nature of your request and your

contact information. Please include the job requisition number in your message

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network

Benefits and Rewards: Read our handbook to learn about all the ways we'll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Division
Biomedical Research

Business Unit
Pharma Research

Location
Switzerland

Site
Basel (City)

Company / Legal Entity
C028 (FCRS = CH028) Novartis Pharma AG

Functional Area
Others

Job Type
Full time

Employment Type
Early Career (Fixed Term)

Shift Work
No